Klump Kelly Square
  • Building: Psychology
  • Office: 107B
  • Phone: (517) 432-7281

Kelly Klump CV

Professor

PhD, Clinical Psychology, University of Minnesota, 1998
MA, Clinical Psychology, University of Minnesota, 1996
BA, , Michigan State University, 1993

Research Statement

The Klump lab studies the etiology of eating disorders. Dr. Klump is particularly interested in understanding developmental differences in genetic and biological risk factors across adolescence and adulthood, with a particular emphasis on the role of gonadal hormones and comorbid traits (e.g., personality traits) and disorders (e.g., mood and anxiety disorders). Dr. Klump's lab approaches these research questions using a translational scientific framework that includes both human and animal studies.

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Selected Publications

  • Racine, S.A., Burt, S.A., Keel, P.K., Sisk, C.L., Neale, M.C., Boker, S., & Klump, K.L.
    Examining associations between negative urgency and key components of objective binge episodes
    2015, International Journal of Eating Disorders
  • Culbert, K.M., Breedlove, S.M., Sisk, C.L., Keel, P.K., Neale, M.C., Boker, S.M., Burt, S.A., & Klump, K.L.
    Age differences in prenatal testosterone’s protective effects on disordered eating symptoms: Developmental windows of expression?
    2015, Behavioral Neuroscience
  • Culbert, K.M., Burt, S.A., Sisk, C.L., Nigg, J.T., & Klump, K.L.
    The effects of circulating testosterone and pubertal maturation on risk for disordered eating symptoms in adolescent males
    2015, Psychological Medicine
  • Hildebrandt, B.A., Racine, S.A., Keel, P.K., Burt, S.A., Neale, M., Boker, S., Sisk, C.L., & Klump, K.L.
    The effects of ovarian hormones and emotional eating on changes in weight preoccupation across the menstrual cycle
    2015, International Journal of Eating Disorders
  • Munn-Chernoff, M.A., Keel, P.K., Klump, K.L., Grant, J.D., Bucholz, K.K., Madden, P.A.F., Heath, A.C., & Duncan, A.E.
    Prevalence and familial influences on purging disorder in a community sample of female twins
    2015, International Journal of Eating Disorders
  • Klump, K.L., Hildebrandt, B.A., O’Connor, S.M., Keel, P.K., Neale, M., Sisk, C.L., Boker, S., & Burt, S.A.
    Changes in genetic risk for emotional eating across the menstrual cycle: A longitudinal study
    2015, Psychological Medicine
  • Slane, J.D., Klump, K.L., McGue, M., & Iacono, W.G.
    Genetic and environmental factors underlying comorbid bulimic behaviors and alcohol use disorders: A moderating role for the dysregulated personality cluster?
    2014, European Eating Disorders Review, 22:159-169
  • Racine, S.E., Culbert, K.M., Burt, S.A., & Klump, K.L.
    Advanced paternal age at birth: Phenotypic and etiologic associations with eating pathology in offspring
    2014, Psychological Medicine, 44:1026-1041
  • Hildebrandt, B.A., Klump, K.L., Racine, S.E., & Sisk, C.L.
    Differential strain vulnerability to binge eating behaviors in rats
    2014, Physiology and Behavior, 127:81-86
  • Klump, K.L., Racine, S.E., Hildebrandt, B., Burt, S.A., Neale, M., Sisk, C.L., Boker, S., & Keel, P.K.
    Ovarian hormone influences on dysregulated eating: A comparison of associations between women with versus without binge episodes
    2014, Clinical Psychological Science, 2:545-559
  • Haedt-Matt, A.A., Keel, P.K., Racine, S.E., Burt, S.A., Hu, J.Y., Boker, S., Neale, M., Sisk, C., & Klump, K.L.
    Do emotional eating urges regulate affect? Concurrent and prospective associations and implications for risk models of binge eating
    2014, International Journal of Eating Disorders, 47:874-877
  • Baker, J.H., Sisk, C.L., Thornton, L., Brandt, H., Crawford, S., Fichter, M.M., Halmi, K.A., Johnson, C., Jones, I., Kaplan, A.S., Mitchell, J.E., Strober, M., Treasure, J., Woodside, D.B., Berrettini, W.H., Kaye, W.H., Bulik, C.M., & Klump, K.L.
    Primary amenorrhea in anorexia nervosa: Impact on characteristic masculine and female traits
    2014, European Eating Disorders Review, 22:32-38
  • Suisman, J.L., Thompson, J.K., Keel, P.K., Burt, S.A., Neale, M., Boker, S., Sisk, C.L., & Klump, K.L.
    Genetic and environmental influences on thin-ideal internalization across puberty and pre-adolescent, adolescent, and young adult development
    2014, International Journal of Eating Disorders, 47:773-783
  • Racine, S.A., Keel, P.K., Burt, S.A., Sisk, C.L., Neale, M., Boker, S., & Klump, K.L.
    Exploring the relationship between negative urgency and dysregulated eating: Etiologic associations and the role of negative affect
    2013, Journal of Abnormal Psychology, 122:433-444
  • Klump, K.L., Keel, P.K., Racine, S.E., Burt, S.A., Sisk, C.L., Neale, M., Boker, S., & Hu, J.Y.
    The interactive effects of estrogen and progesterone on changes in emotional eating across the menstrual cycle
    2013, Journal of Abnormal Psychology, 122:131-137
  • Culbert, K.M., Breedlove, S.M., Nigg, J.T., Sisk, C.L., Burt, S.A., & Klump, K.L.
    The emergence of sex differences in risk for disordered eating attitudes during puberty: A role for prenatal testosterone exposure
    2013, Journal of Abnormal Psychology, 122:420-432
  • Klump, K.L., Keel, P.K., Burt, S.A., Racine, S.E., Neale, M.C., Sisk, C.L., & Boker, S
    Ovarian hormones and emotional eating across the menstrual cycle: An examination of the potential moderating effects of body mass index and dietary restraint
    2013, International Journal of Eating Disorders, 46:256-263
  • Slane, J.D., Klump, K.L., Donnellan, M.B., McGue, M., & Iacono, W.G.
    The dysregulated cluster in personality profiling research: Longitudinal stability and associations with bulimic behaviors and correlates
    2013, Journal of Personality Disorders, 27:337-358
  • Klump, K.L., Racine, S.E., Hildebrandt, B., & Sisk, C.L.
    Sex differences in binge eating proneness in male and female rats
    2013, International Journal of Eating Disorders, 46:729-736
  • Culbert, K.M. Burt, S.A. McGue, M. Iacono, W.G. Klump, K.L.
    Puberty and the genetic diathesis of disordered eating attitudes and behaviors
    2009, Journal of Abnormal Psychology, 118:788-796
  • Klump, K.L.
    Puberty as a critical risk period for eating disorders: A review of human and animal studies
    2013, Hormones and Behavior, 64:399-410
  • Suisman, J.L., O’Connor, S.M., Sperry, S., Thompson, J.K., Keel, P.K., Burt, S.A., Neale, M., Boker, S., Sisk, C., & Klump, K.L.
    Genetic and environmental influences on thin-ideal internalization
    2012, International Journal of Eating Disorders, 45:942-948
  • Racine, S.E., Culbert, K.M., Keel, P.K., Sisk, C.L., Burt, S.A., & Klump, K.L.
    Differential associations between ovarian hormones and disordered eating symptoms across the menstrual cycle in women
    2012, International Journal of Eating Disorders, 45:333-344
  • Burt, S.A. Klump, K.L.
    How Does the Inclusion of Twins Conceived via Fertility Treatments Influence the Results of Twin Studies?
    2012, Twin Research and Human Genetics, 15:746-752
  • Slane, J.D., Burt, S.A., & Klump, K.L.
    Bulimic behaviors and alcohol use: Shared genetic influences
    2012, Behavior Genetics, 42:603-613
  • Klump, K.L., Culbert, K.M., Slane, J.D., Burt, S.A., Sisk, C.L., & Nigg, J.T.
    The effects of puberty on genetic risk for disordered eating: Evidence for a sex difference
    2012, Psychological Medicine, 42:627-638
  • Slane, J.D., Burt, S.A., & Klump, K.L.
    Genetic and environmental influences on depressive and disordered eating symptoms
    2011, International Journal of Eating Disorders, 44:605-611
  • Klump, K.L., Suisman, J.L., Culbert, K.M., Kashy, D.A., & Sisk, C.L.
    Binge eating proneness emerges during puberty in female rats: A longitudinal study
    2011, Journal of Abnormal Psychology, 120:948-955
  • Klump, K.L., Suisman, J.L., Culbert, K.M., Kashy, D.A., Keel, P.K., & Sisk, C.L.
    The effects of ovariectomy on binge eating proneness in adult female rats
    2011, Hormones and Behavior, 59:585-593
  • Racine, S., Burt, S.A., McGue, M., Iacono, W.G., & Klump, K.L.
    Dietary restraint moderates genetic risk for binge eating
    2011, Journal of Abnormal Psychology, 120:119-128
  • Suisman, J.L., Burt, S.A., McGue, M., Iacono, W.G., & Klump, K.L.
    Parental divorce and disordered eating: An investigation of a gene-environment interaction
    2011, International Journal of Eating Disorders, 44:169-177
  • Wang, K., Zhang, H., Bloss, C.T., Duvvuri, V., Kaye, W.H., Schork, N.J., Berrettini, W., Hakonarson, H., Brandt, H., Crawford, S., Crow, S., Fichter, M.M., Halmi, K.A., Johnson, C., Kaplan, A.S., La Via, M., Mitchell, J., Strober, M., Rotondo, A., Treasure, J., Woodside, D.B., Bulik, C.M., Keel, P.K., Klump, K.L., Lilenfeld, L., Thornton, L., Bergen, A.W., & Magistretti, P.
    A genome-wide association on common SNPs and rare CNVs in anorexia nervosa
    2011, Molecular Psychiatry, 16:949-959
  • 106. Root, T. L., Szatkiewicz, J.P., Jonassaint, C.R., Thornton, L.M., Pinheiro, A.P., Sullivan, P., Bloss, C., Berrettini, W.H., Schork, N., Kaye, W.H., Bergen, A., Brandt, H., Crawford, S., Crow, S., Fichter, M.M., Goldman, D., Halmi, K.A., Johnson, C., Kaplan, A.S., Keel, P., Klump, K.L., La Via, M., Mitchell, J., Strober, M., Rotondo, A., Woodside, D.B., & Bulik, C.M.
    Association of candidate genes with phenotypic traits relevant to anorexia nervosa
    2011, European Eating Disorders Review, 19:487-493
  • Klump, K.L., Keel, P.K., Sisk, C.L., & Burt, S.A.
    Preliminary evidence that estradiol moderates genetic effects on disordered eating attitudes and behaviors during puberty
    2010, Psychological Medicine, 40:1745-1754
  • Klump, K.L., Burt, S.A., Spanos, A., McGue, M., Iacono, W.G., & Wade, T.
    Genetic and environmental influences on key eating disorder symptoms: Developmental differences from childhood through middle adulthood for weight and shape concerns
    2010, International Journal of Eating Disorders, 43:679-688
  • Spanos, A., Klump, K.L., Burt, S.A., McGue, M., & Iacono, W.G.
    Nonshared environment and disordered eating: A longitudinal investigation of parent-child conflict
    2010, Journal of Abnormal Psychology, 119:293-299
  • Woods, A.M., Racine, S., & Klump, K.L.
    Examining the relationship between dietary restraint and binge eating: Differential effects of major and minor stressors
    2010, Eating Behaviors, 11:276-280
  • Klump, K.L., Suisman, J., Burt, S.A., McGue, M., & Iacono, W.G.
    Genetic and environmental influences on eating disorder symptoms: An adoption study
    2009, Journal of Abnormal Psychology, 118:797-805
  • Racine, S.E., Culbert, K.M., Larson, C.L., & Klump, K.L.
    Possible moderating effects of impulsivity and dietary restraint on associations between serotonin genes and binge eating
    2009, Journal of Psychiatric Research, 43:1278-1286
  • Culbert, K.M., Burt, S.A., McGue, M., Iacono, W.I., & Klump, K.L.
    Puberty and the genetic diathesis of disordered eating
    2009, Journal of Abnormal Psychology, 118:788-796
  • Klump, K.L., Bulik, C.M., Kaye, W.H., Treasure, J., & Tyson, E.
    Academy for Eating Disorders position paper: Eating disorders are serious mental illnesses
    2009, International Journal of Eating Disorders, 42:97-103
  • Culbert, K.M., S.M.Breedlove, S.A.Burt & K.L.Klump
    Prenatal testosterone exposure and risk for eating disorders: a comparison of opposite-sex and same-sex twins
    2008, Archives of General Psychiatry, 65:329-336
  • Klump, K.L., Culbert, K.M., Edler, C., & Keel, P.K.
    Ovarian hormones and binge eating: Exploring associations in community samples
    2008, Psychological Medicine, 38:1749-1757
  • Suisman, J.L., Slane, J.D., Burt, S.A., & Klump, K.L.
    Negative affect as a mediator of the relationship between weight-based teasing and binge eating in adolescent girls
    2008, Eating Behaviors, 9:493-496
  • Klump, K.L., & Culbert, K.M.
    Molecular genetic studies of eating disorders: Current status and future directions
    2007, Current Directions in Psychological Science, 16:37-41
  • Zehr, J.L., Culbert, K.M., Sisk, C.L., & Klump, K.L.
    Long-term effects of early puberty on disordered eating and anxiety in men and women
    2007, Hormones and Behavior, 52:427-435
  • Klump, K.L., Perkins, P., Burt, S.A., McGue, M., & Iacono, W.G.
    Puberty moderates genetic influences on disordered eating
    2007, Psychological Medicine, 37:627-634
  • Zehr, J.L., Culbert, K.M., Sisk, C.L., & Klump, K.L.
    Long-term effects of early puberty on disordered eating and anxiety in men and women
    2007, Hormones and Behavior, 52:427-435
  • Klump, K.L., Burt, S.A., McGue, M., & Iacono, W.G.
    Changes in genetic and environmental influences on disordered eating across adolescence: A longitudinal twin study
    2007, Archives of General Psychiatry, 64:1409-1415
  • Klump, K.L., & Burt, S.A.
    The Michigan State University Twin Registry (MSUTR): Genetic, environmental, and neurobiological influences on behavior across development
    2006, Twin Research and Human Genetics, 9:971-977
  • Klump, K.L., Gobrogge, K.L., Perkins, P., Thorne, D., Sisk, C.L., & Breedlove, S.M.
    Preliminary evidence that gonadal hormones organize and activate disordered eating
    2006, Psychological Medicine, 36:539-546
  • Klump, K.L., & Gobrogge, K.L
    A review and primer of molecular genetic studies of anorexia nervosa
    2005, International Journal of Eating Disorders, 37:543-548
  • Keel, P.K., Klump, K.L., Miller, K.B., McGue, M., & Iacono, W.G
    Shared transmission of eating disorders and anxiety disorders
    2005, International Journal of Eating Disorders, 38:99-105
  • Bacanu, S-A., Bulik, C.M., Klump, K.L., Fichter, M.M., Halmi, K.A., Keel, P., Kaplan, A.S., Mitchell, J.E., Rotondo, A., Strober, M., Treasure, J., Woodside, D.B., Sonpar, V.A., Xie, W., Bergen, A., Berrettini, W.H., Kaye, W.H., & Devlin, B.
    Linkage analysis of anorexia and bulimia nervosa cohorts using selected behavioral phenotypes as quantitative traits or covariates
    2005, American Journal of Medical Genetics,, 139:61-68
  • Bulik, C.M., Bacanu, S-A., Klump, K.L., Fichter, M.M., Halmi, K.A., Keel, P., Kaplan, A.S., Mitchell, J.E., Rotondo, A., Strober, M., Treasure, J., Woodside, D.B., Sonpar, V.A., Xie, W., Bergen, A., Berrettini, W.H., Kaye, W.H., & Devlin, B.
    Selection of eating-disorder phenotypes for linkage analysis
    2005, American Journal of Human Genetics, 139:81-87
  • Suisman, J.L. Klump, K.L.
    Genetic and neuroscientific perspectives on body image
    2011, Body Image: A Handbook of Science, Practice, and Prevention29-38
  • Klump, K.L., Strober, M., Johnson, C., Thornton, L., Devlin, B., Fichter, M.M., Halmi, K.A., Kaplan, A.S., Woodside, D.B., Crow, S., Mitchell, J., Rotondo, A., Keel, P.K., Berrettini, W.H., Plotnicov, K., Pollice, C., Lilenfeld, L.R., & Kaye, W.H.
    Personality characteristics in women before and after recovery from an eating disorder
    2004, Psychological Medicine, 34:1407-1418
  • Keel, P.K., & Klump, K.L.
    Are eating disorders culture-bound syndromes? Implications for conceptualizing their etiology
    2003, Psychological Bulletin, 129:747-769
  • Klump, K.L., McGue, M., & Iacono, W.G.
    Differential heritability of eating attitudes in pre-pubertal versus pubertal twins
    2003, International Journal of Eating Disorders, 33:287-292
  • Klump, K.L., McGue, M., & Iacono, W.G.
    Genetic relationships between personality and disordered eating
    2002, Journal of Abnormal Psychology, 111:380-389
  • Klump, K.L., Miller, K.B., Keel, P.K., McGue, M., & Iacono, W.G.
    Genetic and environmental influences on anorexia nervosa syndromes in a population-based twin sample
    2001, Psychological Medicine, 31:737-740
  • Klump, K.L., McGue, M., & Iacono, W.G.
    Age differences in genetic and environmental influences on eating attitudes and behaviors in female adolescent twins
    2001, Journal of Abnormal Psychology, 109:239-251
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